The Blood and Wine expansion added a lot to Witcher 3, including new characters, the Skellige Gwent deck, and one of the most beautiful locations in the game, Toussaint. Another excellent addition, though, was the mutations. These powerful new abilities became the focal point of every character build going forward.
There are 12 mutations in total, which all have their own distinct ways of improving the player. But they are not created equal. Some of them are far more useful than others. And as players can only equip one at a time, it’s important to know which are worth spending ability points and mutagens on, and which aren’t.
12 Adrenaline Rush
The main issue with Adrenaline Rush is how long it takes to unlock. Players need to have Piercing Cold and Bloodbath simply to get their hands on this one. And it’s not worth the effort, never mind the mutagens and ability points it costs.
The mutation increases the player’s attack power and sign intensity by 30% per enemy. So if they’re taking on five foes, their damage will be boosted by 150%, which is a lot. But the catch is that it only lasts 30 seconds. After that, it becomes a hindrance as players’ damage drops by 10% per each foe instead.
11 Mutated Skin
With Mutated Skin, each adrenaline point decreases damage received by 15%. So in total, players can improve their defense by 45%.
Not bad, however, there are multiple basic skills that players can pick up to increase their survivability. They shouldn’t have to rely on their mutation and adrenaline points to keep them safe during the most difficult battles in the game. Especially as beyond making them tougher, Mutated skin doesn’t help players in any other way.
10 Toxic Blood
Considering Toxic Blood is one of the cheapest mutations; it’s not that bad. How it works is every time players take a hit in combat, the attacker will receive 1.5% of damage for every point of toxicity the player has. Therefore, if their toxicity bar is full (before it’s enhanced with skills or certain armor), then the people who strike the player will take 150% damage.
That’s a hell of a lot of punishment to deal out just by getting attacked. However, that’s the problem, players need to take a beating to use it, which on harder difficulties is dangerous.
9 Cat Eyes
Every player knows that unless they’re underwater, the crossbow is pretty useless. However, that changes once Cat Eyes is equipped.
The mutation gives a significant increase to the effectiveness of the ranged weapon by boosting its power and critical chance. And in the right hands with some strong bolts, it can turn the crossbow into a truly deadly part of a player’s arsenal. Although, it doesn’t help with the game’s many close-quarters fights.
8 Deadly Counter
The Deadly Counter mutation is fun and deadly at the same time. With it, finishers become a lot more prevalent as counterattacking anyone whose health is below 25% immediately triggers one.
It also gives a 25% boost to sword strikes against those immune to counterattacks as well as all monsters – no matter how strong they are. Those are some decent bonuses, but they aren’t as impressive as what some of the best mutations have to offer.
7 Bloodbath
For every melee strike players land with the Bloodbath mutation equipped, they get a 5% boost to their attack power. Hit enough people, and players can obtain an insane 250% increase in damage.
While it seems incredibly deadly, there is a major drawback. Once players get hit, the boost resets, thus reaching the maximum damage output is rare. But those skilled in the art of dodging and parrying can inflict a lot of pain with this mutation.
6 Second Life
Second Life is like a safety net (albeit one with a 180-second cooldown), as once players die, the mutation makes them invulnerable as their health regens back to 100%.
The usefulness of this depends on the player. A revival power is pointless for those who rarely ever die in the game. Yet, for the players who struggle to contend with all of the creepy monsters roaming around, then this mutation is a literal life-saver.
5 Magic Sensibilities
Despite being one of the cheapest mutations, Magic Sensibilities is up there with the best. It gives players the chance to get a critical hit with their magical signs. And the frequency and damage of those criticals improve based on the sign intensity of the player.
As signs are a significant part of a Witcher’s arsenal, this mutation is a nice way of making them more useful on harder difficulties.
4 Metamorphosis
Metamorphosis is an interesting mutation, as once equipped, every time players apply a critical effect, it randomly triggers a decoction without causing any toxicity. So it’s possible to stack a bunch of the most powerful ones together.
Now, there is a random element to what decoctions are consumed, but it’s only between those that players have previously brewed. Therefore as long as players aren’t making pointless decoctions (they can also drop the useless ones), then it can be very useful. As a bonus, the mutation also gives players better vision in the dark, meaning there’s no need for cat potions or torches.
3 Conductors Of Magic
For players who want to make their signs as powerful as possible, Conductors Of Magic is a necessity.
It adds 50% of their equipped sword’s damage to their sign damage. Although, on the condition that it’s either a magic, unique, or witcher sword, which isn’t much of an issue as those are the best in the game. When the mutation is paired with a sword that has a very big damage output, signs become a lot more lethal than usual.
2 Piercing Cold
When using the Piercing Cold mutation, Aard has a 25% chance of freezing enemies. And once frozen, the opponents die immediately upon hitting the ground. Even those who are lucky enough to avoid the elemental effect still take an incredible amount of damage.
The mutation alone makes Aard extremely effective. But pairing it with skills that boost the strength of the sign makes it one of the most destructive powers in the game.
1 Euphoria
There’s no question that Euphoria is one of the most overpowered abilities in The Witcher 3. Therefore, it’s definitely the most useful mutation. With it, each point of toxicity improves both the player’s sword and sign damage by 0.75%.
Initially, it doesn’t sound like much. However, when paired with skills that increase a player’s maximum toxicity such as Metabolism Control and Acquired Tolerance, and after drinking some strong decoctions, the damage output soon adds up. And players can make quick work of even the toughest opponents in the game.
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