Fans of Capcom‘s Resident Evil franchise love its trademark brand of limited ammunition, zombies at every corner, and a ton of monstrous threats. Moreover, as players will soon learn, almost every outbreak in the series began as a project gone awry from folks at Umbrella Corporation, the de facto “evil organization” in the franchise. However, fans might remember that the games also have their fair share of alternate viruses outside the original T-Virus that plagued the first few games.
In fact, eagle-eyed players might notice that some T-Virus spinoffs seem more dangerous than the original virus. Unfortunately, the forces behind these new strains also want to use them for their own nefarious ends. However, just which viruses in the franchise spark the most terror for players?
10 T-Virus
Interestingly enough, the most popular variant of the Resident Evil virus may turn out to be its least lethal. The T-Virus serves as the template for most of the other viruses in the games. In essence, the T-Virus weaponized the Progenitor Virus, bringing out its resurrection qualities and amplifying the aggression and cannibalistic tendencies of the infected.
However, thanks to the extensive studies and researches conducted on the T-Virus, it’s also one of the easiest viruses to counteract. Moreover, the development of the Daylight Vaccine made the T-Virus the least harmful of the viral agents in the game. Lore-wise, this Daylight Vaccine became part of the standard treatment procedure of outbreaks.
9 Chimera Virus
Dr. Robert Chan developed the Chimera Virus as a solution to the T-Virus and its uncontrollable mutations. With the Chimera Virus, T-Virus infected can now mutate through sheer willpower. This ability will be due to the fact that the Chimera Virus also comes with a means of triggering the part of the human genome that “strives for perfection.”
Unfortunately, not much is known about the Chimera Virus except for its appearance in the BIOHAZARD to the Liberty light novel. Moreover, more potent virus strains began appearing soon afterward.
8 Prototype Virus
Fans of Resident Evil may fondly remember black-clad Albert Wesker and his pair of sunglasses. Moreover, others might call haxx whenever Wesker showed off his incredible strength, speed, and durability against the franchise’s heroes. Thanks to Resident Evil 5, players put a stop to Wesker’s plans once and for all. However, fans mistakenly say Wesker has the Uroboros Virus. In fact, his abilities stemmed from the Prototype Virus, a T-Virus strain that Wesker and other selected participants of Project Wesker had to take.
As part of Umbrella’s eugenics project, the Prototype Virus tested whether particular Project W candidates had the “markers” needed for human evolution. If they don’t, they die from the virus. However, Albert and Alex Wesker survived, with the Prototype Virus giving them more than enough superhuman abilities. Unfortunately, despite the danger the two posed, the difficulty in searching for compatible hosts made the Prototype Virus useless.
7 Chrysalid Virus
The Chrysalid Virus or C-Virus served as The Family’s counterpart to Umbrella’s T-Virus. When Umbrella shut down years prior, the fraternity The Family took it upon themselves to “fulfill” Umbrella’s legacy. Dr. Carla Radames led the project, which involved using a genome that contains elements from the G-Virus and the T-Veronica Virus. As a result, victims not only retained a limited degree of intelligence, but may also manifest extreme mutations depending on genes inserted into them.
The adaptability of the C-Virus made it extremely deadly as a weapon. For instance, The Family’s Derek Simmons used aspects of the C-Virus to force abducted test subjects to “mutate” into clones of Ada Wong. The C-Virus’s approach also allowed The Family to create their own sets of BOWs without the need for cloning, making the C-Virus extremely dangerous if not for the Anti-C Vaccine.
6 Animality Virus
Players of Resident Evil 4 likely remember the Plaga, or the parasite that plagued the village controlled by the Los Illuminados. As it turns out, ex-CIA agent Glenn Arias purchased a Plaga sample and had his team create a virus strain from it. Dubbed the Animality Virus, this strain can create zombies with a “social aspect.”
In turn, the Animality Virus acts very much like the Plaga parasite. Its infected zombies suffer the same aggression and cannibalistic tendencies as T-Virus infected. However, the A-Virus has a slower rate of mental degradation, enabling its infected to retain a certain degree of coordination and speech.
5 Uroboros Virus
Ironically enough, Albert Wesker’s defection from Umbrella helped the defunct company get one step closer to its goal of creating “perfect humans.” Moreover, Wesker and his team developed the Uroboros Virus to create a Progenitor variant more geared towards granting superhuman abilities to the infected. Interestingly, the initial form of the virus became too lethal for any test subject to survive. Thankfully, Jill Valentine’s dormant T-Virus antibodies “balanced” out the Urobos formula.
As a result, Uroboros became an extremely lethal virus that bestows its survivors with superhuman abilities. Uroboros does this by “forcing” its infected to “evolve,” therefore it could only become compatible with a certain population. Thankfully, research into Uroboros halted after Albert and Alex Wesker’s deaths.
4 T-Veronica Virus
Despite “programmable” Tyrants in the Tyrant Project that can follow simple orders, no creature ever “retained” their pre-infection intellect. However, Dr. Alexia Ashford successfully created this much-desired strain with the T-Veronica Virus. Thanks to this strain, its infected not only received the benefits of mutation but also their intellectual capabilities.
Named after Ashford matriarch Veronica, Alexia used ant queens to “fix” the imperfection in the virus strains used on Tyrants. When Alexia used this on herself, she needed an extended incubation period to “perfect” her intellectual retention. Unlike the other viruses, T-Veronica may still force its infected to experience mental degradation. However, this form of mental instability could prove extremely dangerous, as the infected still retained their mental faculties. In turn, a T-Veronica wielder unleashed into the public may become the most dangerous weapon alive.
3 T-Abyss Virus
Despite its short appearance in Revelations, the T-Abyss Virus perhaps posed the most threat out of all the viruses in the franchise. Terrorist group Il Veltro developed the T-Abyss Virus from the Abyss Virus retrovirus endemic to the Kermadec Trench’s Hadopelagic zone. As this implies, the Abyss Virus originally infected fish. In turn, the T-Abyss-Virus-infected not only became zombies but develop traits common to marine wildlife. These include suckers and bloated bodies.
Unfortunately, the T-Abyss can also rapidly mutate its hosts to produce more of it. Moreover, with its preference for water, the T-Abyss may pose a significant threat to the world’s oceans. In fact, estimations indicate that a fifth of the world’s oceans may be affected if the T-Abyss gets released into the world.
2 Golgotha Virus
The G-Virus became the in-house rival of Umbrella USA to the team that developed the T-Virus. However, they’re extremely dissimilar in nature. Whereas the T-Virus caused minor mutations to the infected that created zombies, the G-Virus caused extreme mutations. Moreover, G-Virus infectees are asexually reproductive, enabling them to sprout other “infected”, unlike the T-Virus.
Moreover, whereas T-Virus infectees suddenly develop mutations upon further injury, the G-Virus naturally repairs dead cells. In addition to the extremely violent and durable nature of its hosts, the G-Virus is one of the worst viruses that may cause an outbreak in Resident Evil lore.
1 Progenitor Virus
Found in the Sonnentreppe daisies of West Africa, not much is known about the Progenitor Virus. When Dr. James Marcus, Dr. Brandon Bailey, and Oswell Spencer discovered the Progenitor Virus, they theorized the virus may have been millions or even billions of years old. Moreover, the Progenitor Virus doesn’t affect its victims compared to other known viruses.
The Progenitor Virus not only reverses cell aging, but it can also “revive” organisms that have been considered dead. In turn, this can resurrect bacteria or even people. Unfortunately, infections do eventually lead to death. However, survivors exhibit superhuman abilities, prompting Spencer and company to envision the eugenics project that will lead to the creation of the Umbrella Corporation. Despite its development into the T-Virus, mysteries still remain about the Progenitor Virus and how it can influence the creation of other viruses in the future.
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